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Review
. 2007 Feb;35(2):89-95.
doi: 10.1016/j.gyobfe.2006.12.015. Epub 2007 Feb 2.

[Leptin in pregnancy: facts, questions and future]

[Article in French]
J Lepercq  1 , P Catalano, S Hauguel de Mouzon
Affiliations
Review

[Leptin in pregnancy: facts, questions and future]

[Article in French]
J Lepercq et al. Gynecol Obstet Fertil. 2007 Feb.

Abstract

Leptin has been primarily considered as a protein secreted by the adipocyte and a regulator of satiety and energy homeostasis. A role for leptin in pregnancy was later suggested as circulating levels of leptin are high in the pregnant woman and leptin is synthetized within the placenta. Placental leptin production is increased in various obstetrical conditions associated with alterations of fetal growth (diabetes, preeclampsia). Furthermore, umbilical leptin can be viewed as a biomarker of fetal adiposity. Our aim is to review the putative roles of leptin in pregnancy.

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