Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 Jan;70(1):24-9.
doi: 10.1016/S1726-4901(09)70296-5.

Toward a better understanding of sinonasal mucosal melanoma: clinical review of 23 cases

Yen-Fu Cheng  1 , Chien-Chung Lai, Ching-Yin Ho, Chih-Hung Shu, Ching-Zong Lin
Affiliations
Free article

Toward a better understanding of sinonasal mucosal melanoma: clinical review of 23 cases

Yen-Fu Cheng et al. J Chin Med Assoc. 2007 Jan.
Free article

Abstract

Background: Primary sinonasal mucosal melanoma is a rare disease, occurring far less often than cutaneous lesions. The objective of this study was to review the records of patients diagnosed with primary sinonasal mucosal melanoma.

Methods: We performed a retrospective review of the medical records of 23 patients with sinonasal mucosal melanoma who were treated at Taipei Veterans General Hospital between 1982 and 2002.

Results: Sixteen of the 23 patients were male and 7 were female; their mean age was 68.2 years (range, 39-87 years). At diagnosis, the melanoma was limited to lesions located in the sinonasal area in 20 patients, and had spread in 3 patients. Local recurrence developed in 9 patients, neck metastasis in 5, and distant metastasis in 19. The 5-year disease-specific survival and local control rates were 22.26% and 52.30%, respectively.

Conclusion: In our experience, primary sinonasal mucosa melanoma is prone to spread from the site of origin. The major obstacle in improving overall survival is achieving systemic control.

PubMed Disclaimer