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Comparative Study
. 2007 Feb-Mar;41(1):33-40.
doi: 10.1177/1538574406296246.

Patterns of venous reflux and obstruction in patients with skin damage due to chronic venous disease

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Comparative Study

Patterns of venous reflux and obstruction in patients with skin damage due to chronic venous disease

Nicos Labropoulos et al. Vasc Endovascular Surg. 2007 Feb-Mar.

Abstract

Identified were characteristics of individuals with skin damage related to chronic venous disease. Patients with chronic venous disease (n = 164) were evaluated with duplex ultrasound imaging and were placed in classes 4, 5, and 6 according to the CEAP classification. Their findings were compared with 100 class 2 controls. The prevalence of deep venous thrombosis was higher in the study group (23.7%) versus controls (5.1%; P < .0001), as was the prevalence of deep, perforator, and combined patterns of disease (P < .0001, P < .0007, and P < .0001). The mean duration of disease in controls 2 was shorter compared with the study group (P = .0019). The prevalence of reflux and obstruction within the study group was higher than in controls (P = .0021). Skin changes accurately reflect severity of chronic venous disease. Superficial and perforator vein reflux is the major cause of disease.

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