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Comparative Study
. 1992 Jan;149(1):118-20.
doi: 10.1176/ajp.149.1.118.

Abnormal intracellular calcium ion concentration in platelets and lymphocytes of bipolar patients

S L Dubovsky  1 , J Murphy, M Thomas, J Rademacher
Affiliations
Comparative Study

Abnormal intracellular calcium ion concentration in platelets and lymphocytes of bipolar patients

S L Dubovsky et al. Am J Psychiatry. 1992 Jan.

Abstract

The authors measured intracellular Ca2+ concentrations in four manic and five bipolar depressed patients and seven comparison subjects. Platelet and lymphocyte intracellular Ca2+ concentrations were comparable. The patients' mean intracellular Ca2+ concentrations were higher than those of the comparison subjects and demonstrated more interindividual variation. These findings suggest a diffuse abnormality in mechanisms affecting intracellular calcium homeostasis in bipolar disorder.

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