Characterization of a novel HLA-DRB1*04 allele (DRB1*0460) in the Italian population
- PMID: 17284220
- DOI: 10.1111/j.1744-313X.2006.00641.x
Characterization of a novel HLA-DRB1*04 allele (DRB1*0460) in the Italian population
Abstract
We report the identification of a novel HLA-DRB1*04, officially named DRB1*0460. It was detected during performing HLA-DRB1 high resolution typing by DNA sequencing-based method. The exon 2 nucleotide sequence of DRB1*0460 is identical to that of DRB1*040301 except at codon 63 (AGC-->AAC), changing the encoded serine to asparagine.
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