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. 2007 Feb 9;128(3):425-30.
doi: 10.1016/j.cell.2007.01.021.

Chemical genetics: where genetics and pharmacology meet

Zachary A Knight  1 , Kevan M Shokat
Affiliations
Free article

Chemical genetics: where genetics and pharmacology meet

Zachary A Knight et al. Cell. .
Free article

Abstract

Genetics and pharmacology can elicit surprisingly different phenotypes despite targeting the same protein. This Essay explores these unexpected differences and their implications for biology and medicine.

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