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Review
. 2007 Feb:22:40-6.
doi: 10.1152/physiol.00034.2006.

PKA, germ cells, and fertility

Kimberly A Burton  1 , G Stanley McKnight
Affiliations
Free article
Review

PKA, germ cells, and fertility

Kimberly A Burton et al. Physiology (Bethesda). 2007 Feb.
Free article

Abstract

Temporal and spatial regulation of PKA activity are essential for vigorous sperm motility and for the resumption of meiosis in oocytes, two events required for successful fertilization. Genetic mutations in mice that affect PKA signaling in germ cells lead to infertility and illustrate the importance of this pathway in mammalian reproduction.

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