Evidence for differential regulation of genes in the chondroitin sulfate utilization pathway of Bacteroides thetaiotaomicron
- PMID: 1729221
- PMCID: PMC205717
- DOI: 10.1128/jb.174.1.342-344.1992
Evidence for differential regulation of genes in the chondroitin sulfate utilization pathway of Bacteroides thetaiotaomicron
Abstract
Expression of the chondroitin sulfate utilization (csu) genes of Bacterioides thetaiotaomicron is regulated by chondroitin sulfate. We have now found, however, that the csu genes are not all regulated in the same way. In particular, the gene encoding beta-glucuronidase (csuE) is expressed under two different conditions that do not lead to expression of other csu genes.
Similar articles
-
A locus that contributes to colonization of the intestinal tract by Bacteroides thetaiotaomicron contains a single regulatory gene (chuR) that links two polysaccharide utilization pathways.J Bacteriol. 1992 Nov;174(22):7185-93. doi: 10.1128/jb.174.22.7185-7193.1992. J Bacteriol. 1992. PMID: 1429442 Free PMC article.
-
Cellular location of enzymes involved in chondroitin sulfate breakdown by Bacteroides thetaiotaomicron.J Bacteriol. 1980 Aug;143(2):772-80. doi: 10.1128/jb.143.2.772-780.1980. J Bacteriol. 1980. PMID: 6782076 Free PMC article.
-
Evidence that the Bacteroides thetaiotaomicron chondroitin lyase II gene is adjacent to the chondro-4-sulfatase gene and may be part of the same operon.J Bacteriol. 1987 Mar;169(3):1192-9. doi: 10.1128/jb.169.3.1192-1199.1987. J Bacteriol. 1987. PMID: 3029024 Free PMC article.
-
Comparison of proteins involved in chondroitin sulfate utilization by three colonic Bacteroides species.Appl Environ Microbiol. 1986 May;51(5):978-84. doi: 10.1128/aem.51.5.978-984.1986. Appl Environ Microbiol. 1986. PMID: 3089150 Free PMC article.
-
Chondroitin sulfate/dermatan sulfate sulfatases from mammals and bacteria.Glycoconj J. 2016 Dec;33(6):841-851. doi: 10.1007/s10719-016-9720-0. Epub 2016 Aug 15. Glycoconj J. 2016. PMID: 27526113 Review.
Cited by
-
Use of suppressor analysis to find genes involved in the colonization deficiency of a Bacteroides thetaiotaomicron mutant unable to grow on the host-derived mucopolysaccharides chondroitin sulfate and heparin.Appl Environ Microbiol. 1995 Feb;61(2):734-40. doi: 10.1128/aem.61.2.734-740.1995. Appl Environ Microbiol. 1995. PMID: 7574611 Free PMC article.
-
Mpi recombinase globally modulates the surface architecture of a human commensal bacterium.Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10446-51. doi: 10.1073/pnas.1832655100. Epub 2003 Aug 12. Proc Natl Acad Sci U S A. 2003. PMID: 12915735 Free PMC article.
-
Cloning of a mucin-desulfating sulfatase gene from Prevotella strain RS2 and its expression using a Bacteroides recombinant system.J Bacteriol. 2000 Jun;182(11):3002-7. doi: 10.1128/JB.182.11.3002-3007.2000. J Bacteriol. 2000. PMID: 10809675 Free PMC article.
-
Analysis of two chondroitin sulfate utilization mutants of Bacteroides thetaiotaomicron that differ in their abilities to compete with the wild type in the gastrointestinal tracts of germfree mice.Appl Environ Microbiol. 1992 Mar;58(3):869-76. doi: 10.1128/aem.58.3.869-876.1992. Appl Environ Microbiol. 1992. PMID: 1575488 Free PMC article.
-
A locus that contributes to colonization of the intestinal tract by Bacteroides thetaiotaomicron contains a single regulatory gene (chuR) that links two polysaccharide utilization pathways.J Bacteriol. 1992 Nov;174(22):7185-93. doi: 10.1128/jb.174.22.7185-7193.1992. J Bacteriol. 1992. PMID: 1429442 Free PMC article.
References
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources