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. 2007 Apr 1;17(7):1943-5.
doi: 10.1016/j.bmcl.2007.01.082. Epub 2007 Feb 1.

Anti-formyl peptide antibodies

Fujie Tanaka  1 , Teresa Jones, Diane Kubitz, Richard A Lerner
Affiliations

Anti-formyl peptide antibodies

Fujie Tanaka et al. Bioorg Med Chem Lett. .

Abstract

Antibodies that selectively bind to N-formylmethionyl leucyl phenylalanine (fMLF, also known as fMLP) have been generated. These antibodies bound to fMLF with higher affinity than to non-formylated peptide MLF: the differences in the binding energies between fMLF and MLF were 1.4->2.1 kcal/mol.

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