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. 2007 Feb 12:7:1.
doi: 10.1186/1471-2393-7-1.

Vitamin D status in mothers and their newborns in Iran

Zhila Maghbooli  1 , Arash Hossein-Nezhad, Ali Reza Shafaei, Farzaneh Karimi, Farzaneh Sadat Madani, Bagher Larijani
Affiliations

Vitamin D status in mothers and their newborns in Iran

Zhila Maghbooli et al. BMC Pregnancy Childbirth. .

Abstract

Background: Adequate vitamin D concentrations during pregnancy are necessary to neonatal calcium homeostasis, bone maturation and mineralization. The aim of study is to evaluate serum vitamin D concentrations in mothers and their newborns and effect of vitamin D deficiency on pregnancy outcomes.

Methods: 552 pregnant women were recruited from Tehran University educating hospitals in the winter of 2002. Maternal and cord blood samples were taken at delivery. The serum was assayed for 25-hydroxyvitamin D3, calcium, phosphorus and parathyroid hormone.

Results: The prevalence of vitamin D deficiency in maternal and cord blood samples were 66.8% and 93.3%, respectively (<35 nmol/l). There was significant correlation between maternal and cord blood serum concentrations of vitamin D. In mothers with vitamin D deficiency, cord blood vitamin D concentrations was lower than those from normal mothers (P = .001). Also, a significant direct correlation was seen between maternal vitamin D intake and weight gain during pregnancy.

Conclusion: Consideration to adequate calcium and vitamin D intake during pregnancy is essential. Furthermore, we think it is necessary to reconsider the recommendation for vitamin D supplementation for women during pregnancy.

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