Good players left on the sidelines: why some synaptic vesicles don't get in the game
- PMID: 17296546
- DOI: 10.1016/j.neuron.2007.02.003
Good players left on the sidelines: why some synaptic vesicles don't get in the game
Abstract
A key question in synaptic physiology is what determines the release probability of a synaptic vesicle. In this issue of Neuron, Wadel et al. shed UV light on this problem, finding that hard-to-release vesicles are too far from Ca2+ channels.
Comment on
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The coupling between synaptic vesicles and Ca2+ channels determines fast neurotransmitter release.Neuron. 2007 Feb 15;53(4):563-75. doi: 10.1016/j.neuron.2007.01.021. Neuron. 2007. PMID: 17296557
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