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Case Reports
. 2007 Feb;28(2):316-7.

Imaging cerebral amyloid angiopathy with susceptibility-weighted imaging

E M Haacke  1 , Z S DelProposto, S Chaturvedi, V Sehgal, M Tenzer, J Neelavalli, D Kido
Affiliations
Case Reports

Imaging cerebral amyloid angiopathy with susceptibility-weighted imaging

E M Haacke et al. AJNR Am J Neuroradiol. 2007 Feb.

Abstract

Gradient-echo (GE) imaging is recognized as a means to detect hemorrhagic changes in cerebral amyloid angiopathy (CAA). However, almost 25% of patients with CAA do not show microhemorrhages on T2* GE imaging. We applied a new imaging method, susceptibility weighted imaging (SWI), to evaluate the presence of microhemorrhages. In a suspected case of CAA, where cognitive effects are also present, we show that SWI is much more sensitive in detecting microhemorrhages than conventional methods.

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Figures

Fig 1.
Fig 1.
Axial gradient-echo T2*-weighted image (left; 800/26 ms [TR/TE], 5-mm section thickness, Nx = 256, Ny = 154) shows some low-signal-intensity foci associated with CAA. Corresponding SWI image (right; 85/35 ms [TR/TE], α = 20°, Nx = 512, Ny = 256, with a resolution of 0.5 mm × 0.5 mm × 2.0 mm, projected over 8 mm) shows many more associated low-signal-intensity foci.
See this image and copyright information in PMC

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