Yoghurt containing galacto-oligosaccharides, prunes and linseed reduces the severity of mild constipation in elderly subjects
- PMID: 17299467
- DOI: 10.1038/sj.ejcn.1602670
Yoghurt containing galacto-oligosaccharides, prunes and linseed reduces the severity of mild constipation in elderly subjects
Abstract
Objective: Constipation is a common problem in the elderly. Dietary fibre is recommended for its treatment. The aim was to examine whether yoghurt containing galacto-oligosaccharides (GOS), prunes and linseed relieve constipation in elderly subjects.
Design: A randomized, double-blinded, cross-over study.
Setting: Free-living subjects.
Subjects: A group of 43 elderly subjects with self-reported constipation (mean age 76 years, range 61-92 years, 32 females, 11 males).
Interventions: The study consisted of a 2-week baseline period and 2, 3-week dietary interventions, with a 2-week wash-out period between the interventions. During the interventions, the subjects ingested, in random order, 260 g/day of either control yoghurt or test yoghurt containing GOS (12 g/day), prunes (12 g/day) and linseed (6 g/day). The use of laxatives was controlled and only allowed after 2 days without defecation.
Results: Defecation frequency was 5.7 times/week during the baseline period. During the test yoghurt period, defecation frequency was higher (8.0 vs 7.1 times/week, P=0.011), defecation was easier (on the scale 0-3, 1.3 vs 1.5, P=0.010), and there was a tendency towards softer stools (on the scale 0-3, 2.1 vs 2.2, P=0.059) compared with the control yoghurt period. The subjects felt that the test yoghurt relieved constipation more effectively than the control yoghurt (P=0.005). The sum of gastrointestinal symptoms did not differ between the interventions. The use of laxatives remained constant throughout the study.
Conclusions: Daily intake of yoghurt containing GOS, prunes and linseed reduced the severity of constipation in elderly subjects with mild constipation.
Sponsorship: Valio Ltd, R&D.
Similar articles
-
A combination of fibre-rich rye bread and yoghurt containing Lactobacillus GG improves bowel function in women with self-reported constipation.Eur J Clin Nutr. 2006 Mar;60(3):319-24. doi: 10.1038/sj.ejcn.1602317. Eur J Clin Nutr. 2006. PMID: 16251881 Clinical Trial.
-
Galacto-oligosaccharides relieve constipation in elderly people.Ann Nutr Metab. 1998;42(6):319-27. doi: 10.1159/000012751. Ann Nutr Metab. 1998. PMID: 9895419 Clinical Trial.
-
Pilot study of the feasibility and effectiveness of a natural laxative mixture.Geriatr Nurs. 2007 Mar-Apr;28(2):104-11. doi: 10.1016/j.gerinurse.2006.10.002. Geriatr Nurs. 2007. PMID: 17430744 Clinical Trial.
-
Efficacy and Safety of Over-the-Counter Therapies for Chronic Constipation: An Updated Systematic Review.Am J Gastroenterol. 2021 Jun 1;116(6):1156-1181. doi: 10.14309/ajg.0000000000001222. Am J Gastroenterol. 2021. PMID: 33767108 Free PMC article.
-
Functional constipation.Semin Pediatr Surg. 1995 Feb;4(1):26-34. Semin Pediatr Surg. 1995. PMID: 7728505 Review.
Cited by
-
Modulatory effects of Bifidobacterium longum BB536 on defecation in elderly patients receiving enteral feeding.World J Gastroenterol. 2013;19(14):2162-70. doi: 10.3748/wjg.v19.i14.2162. World J Gastroenterol. 2013. PMID: 23599642 Free PMC article. Clinical Trial.
-
A review of the pharmacobiotic regulation of gastrointestinal inflammation by probiotics, commensal bacteria and prebiotics.Inflammopharmacology. 2012 Oct;20(5):251-66. doi: 10.1007/s10787-012-0126-8. Epub 2012 Mar 18. Inflammopharmacology. 2012. PMID: 22427210 Review.
-
Nutrition and Healthy Aging: Prevention and Treatment of Gastrointestinal Diseases.Nutrients. 2021 Nov 30;13(12):4337. doi: 10.3390/nu13124337. Nutrients. 2021. PMID: 34959889 Free PMC article. Review.
-
Flaxseed powder and magnesium hydroxide syrup on the intestinal function of patients with acute myocardial infarction in intensive care units.Caspian J Intern Med. 2024 Spring;15(2):234-243. doi: 10.22088/cjim.15.2.234. Caspian J Intern Med. 2024. PMID: 38807721 Free PMC article.
-
2022 Seoul Consensus on Clinical Practice Guidelines for Functional Constipation.J Neurogastroenterol Motil. 2023 Jul 30;29(3):271-305. doi: 10.5056/jnm23066. J Neurogastroenterol Motil. 2023. PMID: 37417257 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical