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. 2007 Apr;23(4):129-32.
doi: 10.1016/j.pt.2007.02.001. Epub 2007 Feb 14.

The vaccine is dead--long live the vaccine

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The vaccine is dead--long live the vaccine

Georges Snounou et al. Trends Parasitol. 2007 Apr.

Abstract

An important chapter in the search for a vaccine against malaria, that of the anti-Plasmodium falciparum vaccine candidate SPf66, has been effectively closed. A Cochrane review of ten major efficacy trials in endemic areas concluded it 'has little or no effect on preventing malaria'. This provides an appropriate opportunity to reflect on the perspectives for current and future vaccine formulations against Plasmodium.

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