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. 1975 Nov 21;190(4216):790-2.
doi: 10.1126/science.173019.

Immunosurveillance of naturally occurring feline leukemia

M Essex, A Sliski, S M Cotter, R R Jakowski, W D Hardy Jr

Immunosurveillance of naturally occurring feline leukemia

M Essex et al. Science. .

Abstract

When compared to their housemates that subsequently developed leukemia, cats that remained healthy had five-to tenfold higher (geometric mean) humoral antibody titers to the feline oncornavirus-associated cell membrane antigen. This is compatible with the application of the immunosurveillance hypothesis to the natural development of leukemia in an outbred mammalian species.

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