Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975 Dec 19;190(4220):1200-2.
doi: 10.1126/science.173020.

Tumorigenicity of mouse-human diploid hybrids in nude mice

C M Croce, C Aden, H Koprowski

Tumorigenicity of mouse-human diploid hybrids in nude mice

C M Croce et al. Science. .

Abstract

Somatic cell hybrids between normal mouse cells and simian virus 40 (SV40)-transformed human cells, which contained a diploid complement of mouse chromosomes and the human chromosome 7 carrying the genome of SV40, were tumorigenic in nude mice. One single copy of human chromosome 7 per hybrid cell appeared to be sufficient for the tumorigenicity of the hybrids.

PubMed Disclaimer

Publication types

LinkOut - more resources