Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2007 Jan-Feb;21(1):1-6.
doi: 10.1111/j.1399-0012.2006.00573.x.

Graft-vs.-host disease in lung and other solid organ transplant recipients

Maha A Assi  1 , Jose S Pulido, Steve G Peters, Colin A McCannel, Raymund R Razonable
Affiliations
Review

Graft-vs.-host disease in lung and other solid organ transplant recipients

Maha A Assi et al. Clin Transplant. 2007 Jan-Feb.

Abstract

Graft-vs.-host disease (GVHD) is an uncommon complication of solid organ transplantation. Herein, we report a case of GVHD occurring in a lung transplant recipient and review 29 reported cases of GVHD that complicated thoracic organ, and non-hepatic intra-abdominal organ transplantation. The major presenting clinical symptom of GVHD was skin rash. Less frequent clinical manifestations were cytopenia (16%), diarrhea (11%), and fever (5%). The mainstay of treatment was high-dose corticosteroids. The mortality rate was high (30%). The cause of death was mainly due to infection, suggesting that antimicrobial prophylaxis may improve the outcome of this potentially fatal complication.

PubMed Disclaimer