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. 2007 Feb;56(2):164-5.
doi: 10.1136/gut.2006.105411.

Activation of nuclear factor kappaB in acinar cells does not provoke acute pancreatitis

Roland M Schmid  1
Affiliations

Activation of nuclear factor kappaB in acinar cells does not provoke acute pancreatitis

Roland M Schmid. Gut. 2007 Feb.

Abstract

Acute pancreatitis does not result from nuclear factor κB activation in the pancreas but could inhibition of nuclear factor κB activation be of some benefit in the course of acute pancreatitis?

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Conflict of interest statement

Competing interests: None declared.

References

    1. Grady T, Liang P, Ernst S A.et al Chemokine gene expression in rat pancreatic acinar cells is an early event associated with acute pancreatitis. Gastroenterology 19971131966–1975. - PubMed
    1. Gukovsky I, Gukovskaya A S, Blinman T A.et al Early NF‐kappaB activation is associated with hormone‐induced pancreatitis. Am J Physiol 1998275G1402–G1414. - PubMed
    1. Steinle A U, Weidenbach H, Wagner M.et al NF‐kappaB/Rel activation in cerulein pancreatitis. Gastroenterology 1999116420–430. - PubMed
    1. Gao Y, Lecker S, Post M J.et al Inhibition of ubiquitin‐proteasome pathway‐mediated IκBα degradation by a naturally occurring antibacterial peptide. J Clin Invest 2000106439–448. - PMC - PubMed
    1. Vaquero E, Gukovsky I, Zaninovic V.et al Localized pancreatic NF‐kappaB activation and inflammatory response in taurocholate‐induced pancreatitis. Am J Physiol Gastrointest Liver Physiol 2001280G1197–G1208. - PubMed