[Role of hair follicle stem cell in wound healing and correlative signals]

Abstract

Objective: To review the research progress of hair follicle stem cell (FSC) in wound healing and correlative signals.

Methods: The advances in the FSC location, characters, relations with wound repair and correlative singals were introduced based on the recent related literature.

Results: FSC played an important role in hair follicle cycle and wound healing. The correlative signals maybe Wnt, bone morphogenetic protein/transforming growth factor beta, Norch, Shh and fibroblast growth factor.

Conclusion: The multipotency and plasticity of FSC offer a new way in regeneration medicine and the signals in cell proliferation and differentiation will be the new focus in future research.