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. 1992 Feb;60(2):706-11.
doi: 10.1128/iai.60.2.706-711.1992.

Modified lymphocyte response to mitogens induced by the lipopeptide fragment derived from Mycobacterium avium serovar-specific glycopeptidolipids

S K Tassell  1 , M Pourshafie, E L Wright, M G Richmond, W W Barrow
Affiliations

Modified lymphocyte response to mitogens induced by the lipopeptide fragment derived from Mycobacterium avium serovar-specific glycopeptidolipids

S K Tassell et al. Infect Immun. 1992 Feb.

Abstract

The beta-elimination procedure was used to obtain two major fragments of Mycobacterium avium glycopeptidolipid antigens. The lipopeptide fragment, not the oligosaccharide, diminished the mitogen-induced blastogenic response of spleen cells at concentrations lower than those which affected viability. Electron microscopy revealed an internalization of lipopeptide and disruption of intracellular organization.

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