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Review
. 2007 Feb;26(2):141-3.
doi: 10.1016/j.immuni.2007.02.003.

gp96 leads the way for toll-like receptors

Clifford V Harding  1
Affiliations
Free article
Review

gp96 leads the way for toll-like receptors

Clifford V Harding. Immunity. 2007 Feb.
Free article

Abstract

The role of the gp96 heat-shock protein in regulating Toll-like-receptor expression is incompletely understood. Yang et al. (2007) generated mice with conditional deficiency of gp96 in macrophages and found that this protein is an important chaperone for all Toll-like receptors that have been tested.

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