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. 2007 Apr;73(8):2751-4.
doi: 10.1128/AEM.02459-06. Epub 2007 Feb 16.

Tetracycline resistance mediated by tet(W), tet(M), and tet(O) genes of Bifidobacterium isolates from humans

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Tetracycline resistance mediated by tet(W), tet(M), and tet(O) genes of Bifidobacterium isolates from humans

J Aires et al. Appl Environ Microbiol. 2007 Apr.

Abstract

MICs of tetracyclines were determined for 86 human Bifidobacterium isolates and three environmental strains. The tet(O) gene was found to be absent in these isolates. tet(W) and tet(M) were found in 26 and 7%, respectively, of the Bifidobacterium isolates, and one isolate contained both genes. Chromosomal DNA hybridization showed that there was one chromosomal copy of tet(W) and/or tet(M).

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Figures

FIG. 1.
FIG. 1.
MICs of tetracycline and tet(W)-specific hybridization patterns of PvuII-restricted chromosomal DNA of Bifidobacterium isolates. Not all strains analyzed in this study are included. PM, molecular weight.

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