Tympanic membrane healing in myringotomies performed with argon laser or microknife: an experimental study in rats
- PMID: 17308832
- PMCID: PMC9442066
- DOI: 10.1016/s1808-8694(15)31046-6
Tympanic membrane healing in myringotomies performed with argon laser or microknife: an experimental study in rats
Abstract
Secretory otitis media (SOM) and recurrent acute otitis media (RAOM) may require surgical treatment to proper ventilate the middle ear. Incisional myringotomy is usually done under microscopy with a micro-knife, but it remains patent for just a few days. Recent research indicates that laser assisted myringotomies remain open much longer, allowing middle ear ventilation and healing.
Material and methods: In this experimental study 34 white, male, adult, Wistar rats, without middle ear disease were submitted to anesthesia with ketamine 27 mg/kg and xylazine 2,7 mg/kg. Incisional myringotomy was done on the right ear, while laser myringotomy was done on the left. Myringotomies were evaluated periodically until healing.
Results: The healing times were equivalent. All myringotomies healed within 10 days.
Conclusion: Argon laser assisted myringotomy healed just as early on as incisional myringotomy on Wistar rats without middle ear diseases.
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References
BIBLIOGRAPHY
-
- Stool SE, Bluestone CD. Introduction in studies in otitis media. Ann Otol Rhinol Laryngol. 1988;97(supl 133):6–8.
-
- Soderberg O, Hellstrom, Stenfors LE. Myringotomy made by CO2 laser - An alternative to the ventilation tube? Acta Otolaryngol (Stockh) 1984;97:335–341. - PubMed
-
- Armstrong B. A new treatment for chronic secretory otitis media. Arch Otolaryngol. 1954;59:653. - PubMed
-
- Sederberg-Olsen J, Sederberg-Olsen A, Jensen A. Late results of treatment with ventilation tubes for secretory otitis media in ENT practice. Acta Otolaryngol (Stockh) 1989;108:448–455. - PubMed
-
- Saito H, Miyamoto D, Kishimoto S. Burn perforation as a method of middle ear ventilation. Arch Otolaryngol. 1978;104:79–81. - PubMed
Uncited Reference
-
- Wenzel T. Dissertação de Mestrado, Programa de Pós-Graduação em Medicina: Cirurgia. Universidade Federal do Rio Grande do Sul; 2000. Avaliação do emprego de microeletrocautério na cirurgia da otite média secretora.
-
- Valtonen H, Poe D, Shapshay S. Experimental CO2 laser myringotomy. Otolaryngol Head Neck Surg. 2001;125:161–165. - PubMed
-
- Sedlmaier B, et al. Ventilation time of the middle ear in otitis media with effusion after CO2 laser myringotomy. Laryngoscope. 2002;112:661–668. - PubMed
-
- Cohen D, et al. Laser myringotomy in different age groups. Arch Otolaryngol Head Neck Surg. 2001;127:260–264. - PubMed
-
- Reilly J, Deutsch E, Cook S. Laser-assisted myringotomy for otitis media: A feasibility study with short-term follow-up. Ear Nose Throat J. 2000;79:650–657. - PubMed
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