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Case Reports
. 1975 Dec 8;33(2):165-71.
doi: 10.1007/BF00687542.

Electron microscopic investigation of inclusion material in a case of adult metachromatic leukodystrophy; observations on kidney biopsy, peripheral nerve and cerebral white matter

E Joosten, M Hoes, A Gabreëls-Festen, O Hommes, H Schuurmans Stekhoven, J L Slooff
Case Reports

Electron microscopic investigation of inclusion material in a case of adult metachromatic leukodystrophy; observations on kidney biopsy, peripheral nerve and cerebral white matter

E Joosten et al. Acta Neuropathol. .

Abstract

The fine structural characteristics of storage products in peripheral nerve, kidney and cerebral white matter, from a case of adult metachromatic leukodystrophy are described. There were pronounced differences from the fine structural aspects in late infantile cases. A large proportion of the inclusions did not exhibit a unit membrane. An hypothesis is proposed to clarify the delayed manifestation of this type of metachromatic leukodystrophy until childhood.

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References

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