Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2007 Mar;43(3):107-11.
doi: 10.1111/j.1440-1754.2007.00970.x.

How to use medicines in children: principles of paediatric clinical pharmacology

Yashwant Sinha  1 , Noel E Cranswick
Affiliations
Review

How to use medicines in children: principles of paediatric clinical pharmacology

Yashwant Sinha et al. J Paediatr Child Health. 2007 Mar.

Abstract

Knowledge of drug administration in children and infants has significantly lagged behind that of adults. Despite several paediatric therapeutic mishaps that have been a catalyst for major regulatory reform, the majority of registered medicines do not have indications or dosing for children. This paper will briefly summarise key issues in paediatric pharmacology, including differences in prescribing for children, off-label and unlicensed prescribing and conduct of paediatric clinical trials. A particular emphasis will placed on the situation in Australia.

PubMed Disclaimer