Comment
doi: 10.1016/j.molcel.2007.02.005.
Prolyl cis-trans Isomerization as a molecular timer in Crk signaling
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- PMID: 17317620
- DOI: 10.1016/j.molcel.2007.02.005
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Comment
Prolyl cis-trans Isomerization as a molecular timer in Crk signaling
Mol Cell.
.
Free article
Abstract
In a recent issue of Molecular Cell, use NMR to identify peptidyl-prolyl cis-trans isomerization as an autoinhibitory switch in the adaptor protein Crk, suggesting a new mechanism for controlling the rate of formation of signaling complexes.
Comment on
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Proline cis-trans isomerization controls autoinhibition of a signaling protein.Mol Cell. 2007 Feb 9;25(3):413-26. doi: 10.1016/j.molcel.2007.01.004. Mol Cell. 2007. PMID: 17289588 Free PMC article.
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