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Review
. 2007 Oct-Dec;28(5-6):423-36.
doi: 10.1016/j.mam.2007.01.002. Epub 2007 Jan 11.

Absorption, transport, and tissue delivery of vitamin E

Attilio Rigotti  1
Affiliations
Review

Absorption, transport, and tissue delivery of vitamin E

Attilio Rigotti. Mol Aspects Med. 2007 Oct-Dec.

Abstract

Vitamin E is one of the most abundant lipid-soluble antioxidant agents found in plasma and cells of higher mammals. The uptake, transport and tissue delivery of alpha-tocopherol, a key vitamin E form, involves molecular, biochemical, and cellular processes closely related to overall lipid and lipoprotein homeostasis. This review highlights recent findings that have led to a better understanding of vitamin E transport, including intestinal absorption, hepatic transport, and cellular uptake of alpha-tocopherol in vivo. This new information may be critical for manipulation of vitamin E homeostasis in a variety of oxidative stress-related disease conditions in humans.

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