Centromere assembly and propagation
- PMID: 17320502
- DOI: 10.1016/j.cell.2007.02.002
Centromere assembly and propagation
Abstract
Centromere assembly provides a unique example of how elaborate protein structures can be assembled onto DNA, independent of sequence, and then stably propagated through numerous cell divisions. Here, we review the possible epigenetic strategies that organisms ranging from yeast to human use to assemble and propagate active centromeres.
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