Survival of invasive breast cancer according to the Nottingham Prognostic Index in cases diagnosed in 1990-1999
- PMID: 17321736
- DOI: 10.1016/j.ejca.2007.01.016
Survival of invasive breast cancer according to the Nottingham Prognostic Index in cases diagnosed in 1990-1999
Abstract
The Nottingham Prognostic Index (NPI) is a well established and widely used method of predicting survival of operable primary breast cancer.
Aims: Primary: To present the updated survival figures for each NPI Group. Secondary: From the observations to suggest reasons for the reported fall in mortality from breast cancer.
Methods: The NPI is compiled from grade, size and lymph node status of the primary tumour. Consecutive cases diagnosed and treated at Nottingham City Hospital in 1980-1986 (n=892) and 1990-1999 (n=2,238) are compared. Changes in protocols towards earlier diagnosis and better case management were made in the late 1980s between the two data sets.
Results: Case survival (Breast Cancer Specific) at 10 years has improved overall from 55% to 77%. Within all Prognostic groups there are high relative and absolute risk reductions. The distribution of cases to Prognostic groups shows only a small increase in the numbers in better groups.
Conclusion: The updated survival figures overall and for each Prognostic group for the NPI are presented.
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