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. 1992 Feb;174(3):1050-2.
doi: 10.1128/jb.174.3.1050-1052.1992.

Biosynthesis of vitamin B12 in Pseudomonas denitrificans: the biosynthetic sequence from precorrin-6y to precorrin-8x is catalyzed by the cobL gene product

F Blanche  1 , A Famechon, D Thibaut, L Debussche, B Cameron, J Crouzet
Affiliations

Biosynthesis of vitamin B12 in Pseudomonas denitrificans: the biosynthetic sequence from precorrin-6y to precorrin-8x is catalyzed by the cobL gene product

F Blanche et al. J Bacteriol. 1992 Feb.

Abstract

A protein catalyzing methylation at C-5 and C-15 and decarboxylation of the acetic acid side chain at C-12 on precorrin-6y to yield precorrin-8x was purified to homogeneity from a recombinant strain of Pseudomonas denitrificans. It was sequenced at the N terminus and shown to be encoded by the cobL gene.

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References

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    1. Proc Natl Acad Sci U S A. 1990 Nov;87(22):8795-9 - PubMed
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    1. J Bacteriol. 1992 Feb;174(3):1043-9 - PubMed
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