Comparative Study
doi: 10.1007/BF01317435.
Inhibition of Newcastle disease virus-induced fever in rabbits by cycloheximide
- PMID: 173263
- DOI: 10.1007/BF01317435
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Comparative Study
Inhibition of Newcastle disease virus-induced fever in rabbits by cycloheximide
Arch Virol.
1975.
Abstract
Pretreatment with cycloheximide prevents virus-induced fever in rabbits. Compared to the febrile control animals, CH-pretreated afebrile animals exhibit similar concentrations of endogenous pyrogen in the blood and of prostaglandins of the E-group and adenosine 3', 5'-cycle monophosphate in the cerebrospinal fluid. The fever response seems to involve one or several additional so far unknown mediators which are sensitive to cycloheximide.
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