Awakening from sleep and hypoglycemia in type 1 diabetes mellitus
- PMID: 17326722
- PMCID: PMC1808112
- DOI: 10.1371/journal.pmed.0040099
Awakening from sleep and hypoglycemia in type 1 diabetes mellitus
Abstract
The authors discuss a new study showing that patients with type 1 DM are susceptible to nocturnal hypoglycemia and that there is a relationship between awakening and activation of the counterregulatory response to hypoglycemia.
Conflict of interest statement
Comment on
-
Defective awakening response to nocturnal hypoglycemia in patients with type 1 diabetes mellitus.PLoS Med. 2007 Feb;4(2):e69. doi: 10.1371/journal.pmed.0040069. PLoS Med. 2007. PMID: 17326710 Free PMC article. Clinical Trial.
Similar articles
-
Defective awakening response to nocturnal hypoglycemia in patients with type 1 diabetes mellitus.PLoS Med. 2007 Feb;4(2):e69. doi: 10.1371/journal.pmed.0040069. PLoS Med. 2007. PMID: 17326710 Free PMC article. Clinical Trial.
-
Sleep-related hypoglycemia-associated autonomic failure in type 1 diabetes: reduced awakening from sleep during hypoglycemia.Diabetes. 2003 May;52(5):1195-203. doi: 10.2337/diabetes.52.5.1195. Diabetes. 2003. PMID: 12716752
-
Decreased epinephrine responses to hypoglycemia during sleep.N Engl J Med. 1998 Jun 4;338(23):1657-62. doi: 10.1056/NEJM199806043382303. N Engl J Med. 1998. PMID: 9614256
-
The role of beta-adrenergic sensitivity in the pathogenesis of hypoglycaemia unawareness.Diabetes Nutr Metab. 2002 Oct;15(5):357-61; discussion 361-2. Diabetes Nutr Metab. 2002. PMID: 12625484 Review. No abstract available.
-
Suprachiasmatic nucleus and autonomic nervous system influences on awakening from sleep.Int Rev Neurobiol. 2010;93:91-107. doi: 10.1016/S0074-7742(10)93004-3. Int Rev Neurobiol. 2010. PMID: 20970002 Review.
References
-
- The DCCT Research Group Epidemiology of severe hypoglycemia in the diabetes control and complications trial. Am J Med. 1991;90:450–459. - PubMed
-
- Cryer PE, Davis SN, Shamoon H. Hypoglycemia in diabetes. Diabetes Care. 2003;26:1902–1912. - PubMed
-
- Cryer PE. The pathophysiology of hypoglycaemia in diabetes. Diabetes Nutr Metab. 2002;15:330–333. discussion 62. - PubMed
-
- Gabriely I, Shamoon H. Hypoglycemia in diabetes: Common, often unrecognized. Cleve Clin J Med. 2004;71:335–342. - PubMed
-
- Mellman MJ, Davis MR, Brisman M, Shamoon H. Effect of antecedent hypoglycemia on cognitive function and on glycemic thresholds for counterregulatory hormone secretion in healthy humans. Diabetes Care. 1994;17:183–188. - PubMed
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Medical