Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2007 Mar 3;334(7591):433-4.
doi: 10.1136/bmj.39133.386296.BE.

Folic acid and birth malformations

C Bille, J C Murray, S F Olsen
Editorial

Folic acid and birth malformations

C Bille et al. BMJ. .

Abstract

Despite 15 years of evidence, preventable defects still occur

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Comment on

References

    1. Berry RJ, Li Z, Erickson JD, Li S, Moore CA, Wang H, et al. Prevention of neural-tube defects with folic acid in China. China-US collaborative project for neural tube defect prevention. N Engl J Med 1999;341:1485-90. - PubMed
    1. MRC Vitamin Study Research Group. Prevention of neural tube defects: results of the Medical Research Council vitamin study. Lancet 1991;338:131-7. - PubMed
    1. Wilcox AJ, Lie RT, Solvoll K, Taylor J, McConnaughey DR, Åbyholm F, et al. Folic acid supplements and risk of facial clefts: national population based case-control study. BMJ 2007. doi: 10.1136/bmj.39079.618287.0B - DOI - PMC - PubMed
    1. Bailey LB, Berry RJ. Folic acid supplementation and the occurrence of congenital heart defects, orofacial clefts, multiple births, and miscarriage. Am J Clin Nutr 2005;81:1213S-7S. - PubMed
    1. Badovinac RL, Werler MM, Williams PL, Kelsey KT, Hayes C. Folic acid-containing supplement consumption during pregnancy and risk for oral clefts: a meta-analysis. Birth Defects Res A Clin Mol Teratol 2007;79:8-15. - PubMed