Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1992;59(1):12-6.
doi: 10.1159/000133188.

Isolation and comparative mapping of a human chromosome 20-specific alpha-satellite DNA clone

A Baldini  1 , N Archidiacono, R Carbone, A Bolino, V Shridhar, O J Miller, D A Miller, D C Ward, M Rocchi
Affiliations
Comparative Study

Isolation and comparative mapping of a human chromosome 20-specific alpha-satellite DNA clone

A Baldini et al. Cytogenet Cell Genet. 1992.

Abstract

We have isolated and characterized a human genomic DNA clone (PZ20, locus D20Z2) that identifies, under high-stringency hybridization conditions, an alphoid DNA subset specific for chromosome 20. The specificity was determined using fluorescence in situ hybridization. Sequence analysis confirmed our previously reported data on the great similarity between the chromosome 20 and chromosome 2 alphoid subsets. Comparative mapping of pZ20 on chimpanzee and gorilla chromosomes, also performed under high-stringency conditions, indicates that the alphoid subset has ancestral sequences on chimpanzee chromosome 11 and gorilla chromosome 19. However, no hybridization was observed to chromosomes 21 in the great apes, the homolog of human chromosome 20.

PubMed Disclaimer

Publication types