Review
doi: 10.1016/j.ecl.2006.11.008.
Value of insulin-like growth factor system markers in the assessment of growth hormone status
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- PMID: 17336738
- DOI: 10.1016/j.ecl.2006.11.008
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Review
Value of insulin-like growth factor system markers in the assessment of growth hormone status
Endocrinol Metab Clin North Am.
2007 Mar.
Abstract
Insulin-like growth factor-I (IGF-I) has been measured extensively in a variety of clinical settings. Total IGF-I frequently is used to assess the clinical impact of disorders of GH secretion and to monitor patients' response to therapy. It does not have sufficient precision to be used as a stand-alone test in the diagnosis of GH deficiency. Free IGF-I, IGF binding protein-3, or acid-labile subunit may provide useful information regarding GH secretion in specific conditions but are not superior to IGF-I for making the diagnosis of GH deficiency or acromegaly.
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