Special delivery: dynamic targeting via cortical capture of microtubules
- PMID: 17336896
- DOI: 10.1016/j.devcel.2007.02.012
Special delivery: dynamic targeting via cortical capture of microtubules
Abstract
Gap junction formation depends on the proper transport of connexin hemichannels to sites of cell-cell contact. Recently in Cell, Shaw et al. implicate microtubule tip tracking proteins in the trafficking of connexin43 to adherens junctions (Shaw et al., 2007). This finding suggests a mechanism for targeted delivery of membrane proteins by microtubule capture at the cortex.
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