Mechanical properties of the canine patellar tendon: some correlations with age and the content of collagen

Abstract

Portions of the patellar tendon (PT) are currently used for autogenous and allogeneic reconstruction of a torn or damaged anterior cruciate ligament (ACL). Age-related changes in the mechanical properties of the PT may influence its use in this reconstruction procedure. Age-dependent changes in the PT were determined in the dog, which is often used to experimentally study this reconstruction. Tensile failure experiments were performed at 100% s-1 on patella-patellar tendon-tibia preparations from dogs aged 0.5-15 yr. The contents of collagen soluble and insoluble in pepsin were also measured at each age. Fifty-nine percent (16/27) of the preparations failed by avulsion at the patella, but neither the failure load nor the mode of failure were a function of age. Failure load and energy were higher for tendon substance failures compared to avulsions of bone from the patella. While a positive, linear correlation was measured between tensile modulus of the PT and age, the slope of regression was not significantly different from zero. The content of total collagen in the PT decreased significantly with age. The content of collagen insoluble in pepsin, however, increased with age and positively correlated with tensile modulus of the tendon. These results are different from those reported for the canine CCL, by others, which degenerates with age. Age-related changes in the mechanical properties of the canine PT are qualitatively similar to earlier, limited data on human patellar tendons.(ABSTRACT TRUNCATED AT 250 WORDS)