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Review
. 2007 Mar;39(3):155-62.
doi: 10.1111/j.1745-7270.2007.00263.x.

Structure and function of the NS1 protein of influenza A virus

Dongzi Lin  1 , Jingfang Lan, Zhizhen Zhang
Affiliations
Free article
Review

Structure and function of the NS1 protein of influenza A virus

Dongzi Lin et al. Acta Biochim Biophys Sin (Shanghai). 2007 Mar.
Free article

Abstract

The avian influenza A virus currently prevailing in Asia causes fatal pneumonia and multiple organ failure in birds and humans. Despite intensive research, understanding of the characteristics of influenza A virus that determine its virulence is incomplete. NS1A protein, a non-structural protein of influenza A virus, was reported to contribute to its pathogenicity and virulence. NS1A protein is a multifunctional protein that plays a significant role in resisting the host antiviral response during the influenza infection. This review briefly outlines the current knowledge on the structure and function of the NS1A protein.

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