Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2007 May;24(5):155-8.
doi: 10.1007/s10815-007-9113-1. Epub 2007 Mar 8.

Endometrial thickness and volume by three-dimensional ultrasound one week after embryo transfer to detect pregnancy

Affiliations

Endometrial thickness and volume by three-dimensional ultrasound one week after embryo transfer to detect pregnancy

Wellington Paula Martins et al. J Assist Reprod Genet. 2007 May.

Abstract

Purpose: Determine if the evaluation of endometrium one week after embryo transfer can predict pregnancy.

Methods: Endometrial volume and thickness were evaluated by three-dimensional ultrasound in 40 patients one week after embryo transfer. These results were compared to serum pregnancy test performed one week later.

Results: Eighteen patients have achieved pregnancy. A significant difference was found for endometrial volume: 6.49+/-1.97 mL versus 3.40+/-1.11 mL (pregnant versus not pregnant); and thickness: 11.15+/-2.75 mm versus 9.77+/-1.85 mm. The ROC curve was used to detect the best cutoff values: endometrial volume of 3.48 mL (sensitivity-100%, specificity-68.2%) and endometrial thickness of 10.3 mm (sensitivity-72.2%, specificity-77.3%). The area under curve was significant higher for endometrial volume (0.909 versus 0.745, p=0.027). No pregnancy was achieved in women who had an endometrial volume <3.8 mL (15 patients) or thickness <7.9 mm (3 patients).

Conclusions: The endometrial volume and thickness were significant higher in pregnant women and this difference was more prominent for endometrial volume.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
ROC (Receiver operating characteristic) curves for endometrial volume and thickness evaluated by 3DUS one week after ET to predict pregnancy

Similar articles

Cited by

References

    1. Lambers MJ, Van Weering HG, Van't Grunewold MS, Lambalk CB, Homburg R, Schats R, Hompes PG. Optimizing hCG cut-off values: a single determination on day 14 or 15 is sufficient for a reliable prediction of pregnancy outcome. Eur J Obstet Gynecol Reprod Biol 2006 [Epub ahead of print]. - PubMed
    1. Yong P, Martin C, Thong J. A comparison of psychological functioning in women at different stages of in vitro fertilization treatment using the mean affect adjective check list. J Assist Reprod Genet. 2000;17:553–6. doi: 10.1023/A:1026429712794. - DOI - PMC - PubMed
    1. Keith SC, London SN, Weitzman GA, O’Brien TJ, Miller MM. Serial transvaginal ultrasound scans and beta-human chorionic gonadotropin levels in early singleton and multiple pregnancies. Fertil Steril. 1993;59:1007–10. - PubMed
    1. Raine-Fenning NJ, Clewes JS, Kendall NR, Bunkheila AK, Campbell BK, Johnson IR. The interobserver reliability and validity of volume calculation from three-dimensional ultrasound datasets in the in vitro setting. Ultrasound Obstet Gynecol. 2003;21:283–91. doi: 10.1002/uog.61. - DOI - PubMed
    1. Yaman C, Jesacher K, Polz W. Accuracy of three-dimensional transvaginal ultrasound in uterus volume measurements; comparison with two-dimensional ultrasound. Ultrasound Med Biol. 2003;29:1681–4. doi: 10.1016/S0301-5629(03)01070-6. - DOI - PubMed