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Randomized Controlled Trial
. 2007 May;21(5):747-53.
doi: 10.1007/s00464-007-9217-9. Epub 2007 Mar 7.

Randomized trial of health-related quality of life after open and laparoscopic surgery for colon cancer

Martin Janson  1 , Elisabet Lindholm, Bo Anderberg, Eva Haglind
Affiliations
Randomized Controlled Trial

Randomized trial of health-related quality of life after open and laparoscopic surgery for colon cancer

Martin Janson et al. Surg Endosc. 2007 May.

Abstract

Background: Randomized controlled trials (RCTs) have reported improved or unchanged three-year survival following laparoscopic colon resection (LCR) for colon cancer compared with that following open resection (OCR). The aim of this study was to determine health-related quality of life (HRQL) in patients randomized to laparoscopic or open resection for colon cancer.

Methods: In total, 285 patients (130 LCR, 155 OCR) from seven Swedish centers were included. HRQL was assessed preoperatively and at 2, 4, and 12 weeks postoperatively with the EQ-5D and EORTC QLQ-C30 instruments.

Results: The LCR patients did significantly better on the social function component of the EORTC QLQ-C30 at two and four weeks and on the role function component at two weeks.

Conclusion: Laparoscopic resection for colon cancer improved quality of life during the first postoperative month.

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