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Review
. 2006 Oct;26(5):281-6.

Endoscopic treatment of gastro-oesophageal reflux disease

M A Bianco  1 , G Rotondano, M L Garofano, L Cipolletta
Affiliations
Review

Endoscopic treatment of gastro-oesophageal reflux disease

M A Bianco et al. Acta Otorhinolaryngol Ital. 2006 Oct.

Abstract
in English, Italian

Gastro-oesophageal reflux disease is a common chronic disorder which has a severe effect on the patient's quality of life. In view of the high cost of medical therapy and the limitations of surgery, a variety of endoscopic techniques have been developed for the treatment of this condition, and these have shown apparently encouraging results, at least in the short- term. However, several inconsistencies have emerged between the efficacy of endoscopic treatment in improving symptoms and quality of life and a lack of improvement of objective parameters. Controlled studies are urgently needed in order to clarify the potential of endoscopic therapy. Currently, the use of endoscopic treatment should be limited to clinical trials.

La malattia da reflusso gastroesofageo è un disordine frequente di tipo cronico recidivante con notevole impatto sulla qualità di vita dei pazienti. Dati i costi elevati della terapia farmacologica ed i limiti della terapia chirurgica, è stato sviluppato un certo numero di trattamenti endoscopici che hanno dimostrato risultati incoraggianti nel breve termine. Ciononostante, sono emerse alcune incongruenze tra efficacia clinica e mancanza di miglioramento dei parametri funzionali (esposizione acida esofagea, ecc.); pertanto vi è urgenza di studi clinici controllati che chiariscano il vero potenziale di questo tipo di trattamento. Al momento, la terapia endoscopica del reflusso deve essere valutata nell’ambito di trials clinici.

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Figures

Fig. 1
Fig. 1
Schematic picture of the Stretta procedure. Delivery catheter in situ with needles into the muscle layer of the LES (A); sites of RF energy lesions (B).
See this image and copyright information in PMC

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