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Review
. 2007 Feb;65(2):88-94.
doi: 10.1111/j.1753-4887.2007.tb00285.x.

Dietary components impact histone modifications and cancer risk

Cindy D Davis  1 , Sharon A Ross
Affiliations
Review

Dietary components impact histone modifications and cancer risk

Cindy D Davis et al. Nutr Rev. 2007 Feb.

Abstract

Epigenetics refers to the study of heritable changes in gene expression that occur without a change in the DNA sequence and constitute an important mechanism by which dietary components can selectively activate or inactivate gene expression. Alterations in histone acetylation and methylation are a common hallmark of human cancer. This review focuses on several histone-modifying enzymes that are associated with cancer development and their modification by bioactive food components.

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