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. 2007 Mar;89(2):127-9.
doi: 10.1308/003588407X155789.

Cancer genetics clinics and the surgeon: a valuable role for family history screening

G L Williams  1 , J Gray, J Beynon
Affiliations

Cancer genetics clinics and the surgeon: a valuable role for family history screening

G L Williams et al. Ann R Coll Surg Engl. 2007 Mar.

Abstract

Introduction: This study examines how a colorectal surgeon can use a regional cancer genetics service to deal safely and efficiently, with community referrals for colorectal cancer screening on the basis of family history.

Patients and methods: A retrospective review of consecutive asymptomatic people with a strong family of colorectal cancer referred by the surgeon to the genetics service over a 30-month period.

Results: A total of 45 people were referred by the surgeon to the cancer genetics service. Following official verification of family histories, 15 were thought to be in a low-risk category for developing colorectal cancer, 18 were moderate risk, 4 had a high-to-moderate risk and 2 satisfied the criteria for HNPCC. After official authentication, it was discovered that 20% of people had mistakenly informed the surgeon of important inaccuracies in their family history.

Conclusions: The cancer genetics service seeks to identify accurately those at increased risk of developing colorectal cancer due to their family history. It has the time, resources and expertise to verify officially a family history that cannot be properly done in a busy surgical clinic. This study shows that it can provide a valuable role for correctly identifying and counselling people who truly require screening due to their familial predisposition for colorectal cancer.

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Figure 1
Figure 1
Pathway for colorectal family history referrals.
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References

    1. Love RR, Evans AM, Josten DM. The accuracy of patient reports of a family history of cancer. J Chronic Dis. 1985;38:289–93. - PubMed
    1. Scholefield JH, Johnson AG, Shorthouse AJ. Current surgical practice in screening for colorectal cancer based on family history criteria. Br J Surg. 1998;85:1543–6. - PubMed
    1. Dunlop MG. Guidelines for colorectal cancer screening in high risk groups. Gut. 2002;51(Suppl V):v17–20. - PMC - PubMed
    1. Aitken J, Bain C, Ward M, Siskind V, MacLennan R. How accurate is self-reported family history of colorectal cancer. Am J Epidemiol. 1995;141:863–71. - PubMed
    1. Ruo L, Cellini C, La-Calle JP, Jr, Murray M, Thaler HT, Quan SHQ, et al. Limitations of family cancer history assessment at initial surgical consultation. Dis Colon Rectum. 2001;44:98–104. - PubMed