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. 2007 Mar;196(3):206-12.
doi: 10.1016/j.ajog.2007.01.028.

Review of the economic and quality-of-life burden of cervical human papillomavirus disease

Rachael L Fleurence  1 , Julia M Dixon, Tsveta F Milanova, Kathleen M Beusterien
Affiliations

Review of the economic and quality-of-life burden of cervical human papillomavirus disease

Rachael L Fleurence et al. Am J Obstet Gynecol. 2007 Mar.

Abstract

Objective: The purpose of this study was to conduct a systematic literature review on the economic burden and health-related quality-of-life impact of cervical human papillomavirus disease.

Study design: A systematic review of cost-of-illness studies and health-related quality-of-life studies was conducted. PubMed, Embase, and PsycINFO databases were searched with the use of predefined terms.

Results: Nine economic and 24 quality-of-life studies were identified. The annual health care costs of human papillomavirus-related conditions in the United States range from 2.25-4.6 billion dollars (2005 US dollars). The burden of human papillomavirus is second only to human immunodeficiency virus among sexually transmitted diseases. Health-related quality-of-life areas that are impacted substantially by human papillomavirus include emotional, social, and sexual functioning.

Conclusion: The economic and quality-of-life burden of cervical human papillomavirus disease is significant and highlights the need for treatment and prevention options for this condition.

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