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Case Reports
. 2007 Apr;42(4):393-6.
doi: 10.1002/ppul.20595.

Acute life threatening event (ALTE) in an infant with human coronavirus HCoV-229E infection

Arne Simon  1 , Sebastian Völz, Katja Höfling, Alexandra Kehl, Ramona Tillman, Andreas Müller, Bernd Kupfer, Anna-Maria Eis-Hübinger, Michael J Lentze, Udo Bode, Oliver Schildgen
Affiliations
Case Reports

Acute life threatening event (ALTE) in an infant with human coronavirus HCoV-229E infection

Arne Simon et al. Pediatr Pulmonol. 2007 Apr.

Abstract

In this short report we discuss the temporal association between an acute life threatening event (ALTE) and a RT-PCR confirmed coronavirus HCoV-229E infection in a 4 months old otherwise healthy infant. More detailed microbiological investigations of affected children even without apparent signs of a respiratory tract infection may help to clarify the etiology in some patients and extend our understanding of the pathogenesis. PCR-based techniques should be utilized to increase the sensitivity of detection for old and new respiratory viral pathogens in comparable cases.

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