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Comparative Study
. 2006 Jun;141(6):688-90.
doi: 10.1007/s10517-006-0253-6.

Protective effect of complex antioxidant preparation containing vitamins and amino acids in rats with burn trauma complicated by endotoxemia

[Article in English, Russian]
E V Mikhal'chik  1 , S M Titkova, M V Anurov, A P Ettinger, L G Korkina
Affiliations
Comparative Study

Protective effect of complex antioxidant preparation containing vitamins and amino acids in rats with burn trauma complicated by endotoxemia

[Article in English, Russian]
E V Mikhal'chik et al. Bull Exp Biol Med. 2006 Jun.

Abstract

Burn trauma increased blood chemiluminescence, while lipopolysaccharide in a dose of 1 mg/kg potentiated this effect, activated LPO, and decreased plasma antioxidant activity. In erythrocytes, superoxide dismutase activity increased, while activity of peroxide-utilizing enzymes decreased. Myeloperoxidase content increased in the lungs and epidermis. The preparation of alpha-tocopherol, selenium aspartate, and ubiquinone abolished the effect of lipopolysaccharide, but did not modulate the increase in chemiluminescence under the influence of this agent.

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