doi: 10.1080/01485010600908330.
Sperm survival: relationship to age-related sperm DNA integrity in infertile men
Affiliations
- PMID: 17364462
- DOI: 10.1080/01485010600908330
Item in Clipboard
Sperm survival: relationship to age-related sperm DNA integrity in infertile men
Arch Androl.
2007 Jan-Feb.
Abstract
The purpose of our study was to evaluate the effect of age and sperm DNA integrity on sperm survival. Semen samples from fifty six unselected patients undergoing infertility evaluation were assessed in terms of standard semen parameters, DNA integrity, and sperm survival after 6-24 h of incubation. Prolonged incubation of density gradient selected sperm adversely effects sperm survival in older patients and patients with extensive sperm DNA damage. Immediate preparation of such samples prior to use for assisted reproductive technology (ART) may overcome the negative effect of extended incubation.
Similar articles
-
Effect of leukocytospermia on sperm DNA integrity: a negative effect in abnormal semen samples.J Androl. 2002 Sep-Oct;23(5):717-23. J Androl. 2002. PMID: 12185107
-
Relationship between seminal ascorbic acid and sperm DNA integrity in infertile men.Int J Androl. 2006 Dec;29(6):569-75. doi: 10.1111/j.1365-2605.2006.00700.x. Int J Androl. 2006. PMID: 17121654
-
Mitochondrial DNA integrity and copy number in sperm from infertile men.Fertil Steril. 2008 Dec;90(6):2238-44. doi: 10.1016/j.fertnstert.2007.10.059. Epub 2008 Feb 4. Fertil Steril. 2008. PMID: 18249386
-
Sperm DNA damage and its clinical relevance in assessing reproductive outcome.Asian J Androl. 2004 Jun;6(2):139-48. Asian J Androl. 2004. PMID: 15154089 Review.
-
Sperm DNA damage: importance in the era of assisted reproduction.Curr Opin Urol. 2006 Nov;16(6):428-34. doi: 10.1097/01.mou.0000250283.75484.dd. Curr Opin Urol. 2006. PMID: 17053523 Review.
Cited by
-
Effects of Antiretroviral Therapy on Sperm DNA Integrity of HIV-1-Infected Men.Am J Mens Health. 2018 Nov;12(6):1835-1842. doi: 10.1177/1557988318794282. Epub 2018 Aug 22. Am J Mens Health. 2018. PMID: 30132391 Free PMC article.
-
Impact of metabolic syndrome on the viability of human spermatozoa: a cross-sectional descriptive study in men from infertile couples.Basic Clin Androl. 2021 Oct 7;31(1):22. doi: 10.1186/s12610-021-00142-8. Basic Clin Androl. 2021. PMID: 34615459 Free PMC article.
-
Spermatozoal sensitive biomarkers to defective protaminosis and fragmented DNA.Reprod Biol Endocrinol. 2007 Aug 30;5:36. doi: 10.1186/1477-7827-5-36. Reprod Biol Endocrinol. 2007. PMID: 17760963 Free PMC article. Review.
-
Effects of men and recipients' age on the reproductive outcome of an oocyte donation program.J Assist Reprod Genet. 2008 Sep-Oct;25(9-10):445-52. doi: 10.1007/s10815-008-9255-9. Epub 2008 Oct 7. J Assist Reprod Genet. 2008. PMID: 18839305 Free PMC article.
MeSH terms
Substances
LinkOut - more resources
Medical