PPARalpha and effects of TCE
- PMID: 17366801
- PMCID: PMC1797851
- DOI: 10.1289/ehp.115-1797851
PPARalpha and effects of TCE
Comment on
-
Key issues in the role of peroxisome proliferator-activated receptor agonism and cell signaling in trichloroethylene toxicity.Environ Health Perspect. 2006 Sep;114(9):1464-70. doi: 10.1289/ehp.8693. Environ Health Perspect. 2006. PMID: 16966106 Free PMC article. Review.
Similar articles
-
Key issues in the role of peroxisome proliferator-activated receptor agonism and cell signaling in trichloroethylene toxicity.Environ Health Perspect. 2006 Sep;114(9):1464-70. doi: 10.1289/ehp.8693. Environ Health Perspect. 2006. PMID: 16966106 Free PMC article. Review.
-
The Contribution of Peroxisome Proliferator-Activated Receptor Alpha to the Relationship Between Toxicokinetics and Toxicodynamics of Trichloroethylene.Toxicol Sci. 2015 Oct;147(2):339-49. doi: 10.1093/toxsci/kfv134. Epub 2015 Jul 1. Toxicol Sci. 2015. PMID: 26136231 Free PMC article.
-
Role of the peroxisome proliferator-activated receptor alpha (PPARalpha) in responses to trichloroethylene and metabolites, trichloroacetate and dichloroacetate in mouse liver.Toxicology. 2004 Oct 15;203(1-3):83-98. doi: 10.1016/j.tox.2004.06.014. Toxicology. 2004. PMID: 15363585
-
The Role of miR-182-5p in Hepatocarcinogenesis of Trichloroethylene in Mice.Toxicol Sci. 2017 Mar 1;156(1):208-216. doi: 10.1093/toxsci/kfw246. Toxicol Sci. 2017. PMID: 28013219
-
The use of mechanistic data and the handling of scientific uncertainty in carcinogen risk assessments. The trichloroethylene example.Regul Toxicol Pharmacol. 2002 Feb;35(1):80-94. doi: 10.1006/rtph.2001.1508. Regul Toxicol Pharmacol. 2002. PMID: 11846638 Review.
References
-
- Akiyama TE, Nicol CJ, Fievet C, Staels B, Ward JM, Auwerx J, et al. Peroxisome proliferator-activated receptor-alpha regulates lipid homeostasis, but is not associated with obesity: studies with congenic mouse lines. J Biol Chem. 2001;276:39088–39093. - PubMed
-
- Anderson SP, Dunn C, Laughter A, Yoon L, Swanson C, Stulnig TM, et al. Overlapping transcriptional programs regulated by the nuclear receptors peroxisome proliferator-activated receptor alpha, retinoid X receptor, and liver X receptor in mouse liver. Mol Pharmacol. 2004a;66:1440–1452. - PubMed
-
- Anderson SP, Howroyd P, Liu J, Qian X, Bahnemann R, Swanson C, et al. The transcriptional response to a peroxisome proliferator-activated receptor alpha agonist includes increased expression of proteome maintenance genes. J Biol Chem. 2004b;279:52390–52398. - PubMed
-
- Cheung C, Akiyama TE, Ward JM, Nicol CJ, Feigenbaum L, Vinson C, et al. Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor alpha. Cancer Res. 2004;64:3849–3854. - PubMed
-
- Hays T, Rusyn I, Burns AM, Kennett MJ, Ward JM, Gonzalez FJ, et al. Role of peroxisome proliferator-activated receptor-alpha (PPARalpha) in bezafibrate-induced hepatocarcinogenesis and cholestasis. Carcinogenesis. 2005;26:219–227. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources