PPARalpha and effects of TCE
- PMID: 17366801
- PMCID: PMC1797851
- DOI: 10.1289/ehp.115-1797851
PPARalpha and effects of TCE
Comment on
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Key issues in the role of peroxisome proliferator-activated receptor agonism and cell signaling in trichloroethylene toxicity.Environ Health Perspect. 2006 Sep;114(9):1464-70. doi: 10.1289/ehp.8693. Environ Health Perspect. 2006. PMID: 16966106 Free PMC article. Review.
References
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- Anderson SP, Dunn C, Laughter A, Yoon L, Swanson C, Stulnig TM, et al. Overlapping transcriptional programs regulated by the nuclear receptors peroxisome proliferator-activated receptor alpha, retinoid X receptor, and liver X receptor in mouse liver. Mol Pharmacol. 2004a;66:1440–1452. - PubMed
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- Anderson SP, Howroyd P, Liu J, Qian X, Bahnemann R, Swanson C, et al. The transcriptional response to a peroxisome proliferator-activated receptor alpha agonist includes increased expression of proteome maintenance genes. J Biol Chem. 2004b;279:52390–52398. - PubMed
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- Cheung C, Akiyama TE, Ward JM, Nicol CJ, Feigenbaum L, Vinson C, et al. Diminished hepatocellular proliferation in mice humanized for the nuclear receptor peroxisome proliferator-activated receptor alpha. Cancer Res. 2004;64:3849–3854. - PubMed
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- Hays T, Rusyn I, Burns AM, Kennett MJ, Ward JM, Gonzalez FJ, et al. Role of peroxisome proliferator-activated receptor-alpha (PPARalpha) in bezafibrate-induced hepatocarcinogenesis and cholestasis. Carcinogenesis. 2005;26:219–227. - PubMed
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