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. 2007 Jan;115(1):75-9.
doi: 10.1289/ehp.9223.

Increased rate of hospitalization for diabetes and residential proximity of hazardous waste sites

Maria Kouznetsova  1 , Xiaoyu Huang, Jing Ma, Lawrence Lessner, David O Carpenter
Affiliations

Increased rate of hospitalization for diabetes and residential proximity of hazardous waste sites

Maria Kouznetsova et al. Environ Health Perspect. 2007 Jan.

Abstract

Background: Epidemiologic studies suggest that there may be an association between environmental exposure to persistent organic pollutants (POPs) and diabetes.

Objective: The aim of this study was to test the hypothesis that residential proximity to POP-contaminated waste sites result in increased rates of hospitalization for diabetes.

Methods: We determined the number of hospitalized patients 25-74 years of age diagnosed with diabetes in New York State exclusive of New York City for the years 1993-2000. Descriptive statistics and negative binomial regression were used to compare diabetes hospitalization rates in individuals who resided in ZIP codes containing or abutting hazardous waste sites containing POPs ("POP" sites); ZIP codes containing hazardous waste sites but with wastes other than POPs ("other" sites); and ZIP codes without any identified hazardous waste sites ("clean" sites).

Results: Compared with the hospitalization rates for diabetes in clean sites, the rate ratios for diabetes discharges for people residing in POP sites and "other" sites, after adjustment for potential confounders were 1.23 [95% confidence interval (CI), 1.15-1.32] and 1.25 (95% CI, 1.16-1.34), respectively. In a subset of POP sites along the Hudson River, where there is higher income, less smoking, better diet, and more exercise, the rate ratio was 1.36 (95% CI, 1.26-1.47) compared to clean sites.

Conclusions: After controlling for major confounders, we found a statistically significant increase in the rate of hospitalization for diabetes among the population residing in the ZIP codes containing toxic waste sites.

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Figures

Figure 1
Figure 1
Map of distribution of the waste sites in NYS by ZIP code.
Figure 2
Figure 2
Crude (unadjusted) hospitalization rates for diabetes before modeling for all of the NYS population (except NYC) for ages 25–74 years in clean, “other,” and POP sites (A) and broken down by age (B). The numbers above the bars indicate the rates per 100,000. *Statistically significant compared to clean sites (p < 0.05 ).
See this image and copyright information in PMC

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References

    1. Agency for Toxic Substances and Disease Registry. http://www.atsdr.cdc.gov/toxprofiles/tp17.html - PubMed
    1. Al-Moosa S, Allin A, Jemiai N, Al-Lawati J, Mossialos E. Diabetes and urbanization in the Omani population: an analysis of national survey data. Popul Health Metr. 2006;4:5. - PMC - PubMed
    1. Ashton CM, Petersen NJ, Souchek J, Menke TJ, Yu HJ, Pietz K, et al. Geographic variations in utilization rates in Veterans Affairs hospitals and clinics. N Engl J Med. 1999;340:32–39. - PubMed
    1. Bertazzi PA, Bernucci I, Brambilla G, Consonni D, Pesatori AC. The Seveso studies on early and long-term effects of dioxin exposure: a review. Environ Health Perspect. 1998;106(suppl 2):625–633. - PMC - PubMed
    1. Boll M, Webber LWD, Messner B, Stampfl A. Polychlorinated biphenyls affect the activities of gluconeogenic and lipogenic enzymes in rat liver: is there an interference with regulatory hormone actions? Xenobiotica. 1998;28:479–492. - PubMed

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